Increased M1 macrophages in young miR-15a/16−/− mice with tumour grafts or dextran sulphate sodium-induced colitis
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چکیده
منابع مشابه
Protective Effects of Pioglitazone against Dextran Sodium Sulphate-Induced Colitis in Rats.
The aim of the present study is to investigate the preventive effect of pioglitazone on colitis induced with dextran sulfate sodium (DSS) in rats. Twenty-four male Sprague-Dawley rats weighing 180-200 g were randomized into four groups. Rats of the 1st group received only saline and served as normal group. Colitis was induced in the remaining 3 groups by 1.5% DSS administered in drinking water ...
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One of the main treatments currently used in humans to fight cancer is chemotherapy. A huge number of compounds with antitumor activity are present in nature, and many of their derivatives are produced by microorganisms. However, the search for new drugs still represents a main objective for cancer therapy, due to drug toxicity and resistance to multiple chemotherapeutic drugs. In animal models...
متن کاملDevelopment of colonic neoplasia in p53 deficient mice with experimental colitis induced by dextran sulphate sodium.
BACKGROUND Several animal models for human ulcerative colitis (UC) associated neoplasia have been reported. However, most neoplasias developed in these models have morphological and genetic characteristics different from UC associated neoplasia. AIMS To establish a new colitis associated neoplasia model in p53 deficient mice by treatment with dextran sulphate sodium (DSS). METHODS DSS colit...
متن کاملEffects of Guchang Capsule on Dextran Sulphate Sodium-Induced Experimental Ulcerative Colitis in Mice
Guchang capsule (GC) is a Chinese materia medica standardized product extracted from 15 Chinese traditional medical herbs and it has been clinically used in the treatment of intestinal disease. In this study, in order to extend the research of GC in intestinal disease, we were aiming to evaluate potential effects of GC on dextran sulphate sodium- (DSS-) induced murine experimental colitis and t...
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ژورنال
عنوان ژورنال: Scandinavian Journal of Immunology
سال: 2018
ISSN: 0300-9475
DOI: 10.1111/sji.12703